Invited conferences
Imaging biomarkers for CNS drug development
Creatin Transporter Deficiency (CTD) Symposium 2023, Paris, France
Imaging the neuro-vascular transport and coupling for translational pharmacology
Cerebro-vascular Biology, CVB 2023, Uppsala, Sweden
Imaging for Pharmacokinetics : improving our understanding of drug distribution to tissues in humans
Institut Paris-Saclay d'innovation thérapeutique, Chatenay-Malabry, France, November 2020
Imaging in neuropharmacology: applications to clinical toxicology
40th International Congress of the European Association of Poisons Centres and Clinical Toxicologists (EAPCCT), Tallin, Estonia, June 2020
Demonstrating importance of membrane transporters in tissue distribution of drugs using clinical imaging techniques
Biomedicum Helsinki Seminars, Helsinki, Finland, March 2020
Imaging and radiopharmaceuticals for a new insight into pharmacokinetics
French Academy of Pharmacy, February 2020
Imaging techniques to study drug transport function in vivo
Hepatocyte Transporter Network, Les Diablerets, Switzerland, September 2019
PET Imaging for In Vivo Determination of Pharmacokinetic Parameters
Gordon Research Conference, Drug Metabolism, Holderness, NH, USA, July 2019
Contributions of PET Imaging of ABC Transporters at the Blood-Brain Barrier to the Evaluation of Psychotropic Drugs
EANM'18, Annual Congress of the European Association of Nuclear Medicine, Germany, October 2018.
Exploring blood-brain barrier function using positron emission tomography
Society for the study of blood-brain interface
Tours, France - November 2017
18F-FDG in epilepsy: what the epileptologist has to know?
First International Course on PET in Epilepsy
Orsay, France - June 2017
Imagerie des transporteurs membranaires : implications pharmacocinétiques
Service Immunologie des Infections Virales et des Maladies Auto-immunes (IMVA),
Kremlin-Bicêtre, France - February 2017
Imaging drug pharmacokinetics
Paris-Saclay PIM Workshop, Pharmacological Imaging and Multi-modality
Orsay, France - December 2015
Influence of drug transporters on PET and SPECT tracer kinetics: implication for imaging data interpretation
SFB35 Transmembrane Transporters in Health and Disease
Vienna, Austria - October 2014
Oral communications
Early impact of antidepressant treatments on synaptic density in a mouse model of anxiety/depression: a synaptic vesicle protein 2a (SV2A) positron emission tomography (PET) imaging study
Cassandre M. Corvo, Sebastien Goutal, Indira Mendez-David, Maud Goislard, Sophie Amargier, Sarah Leterrier, Claire Leroy, Denis J. David, Nicolas Tournier1
EMIM, Porto, 2024
Importance of OATP function for the pharmacokinetic variability associated with sex and age : a whole-body dynamic PET study using 11C-glyburide
MARIE Solène, LECOQ Anne-Lise, BREUIL Louise, CHALAMPALAKIS Zacharias, BECQUEMONT Laurent, CAILLÉ Fabien, GERVAIS Philippe, LEBON Vincent, COMTAT Claude, BOTTLAENDER Michel, VERSTUYFT Céline, TOURNIER Nicolas
PET is wondeful ! Edimburg, 2023
18F-FDS PET imaging as a quantitative marker to investigate the magnitude and dynamics of enhanced of BBB permeability induced by regadenoson , an agonist of adenosine A 2 receptors
B. Hosten, S. Goutal, N. Tournier
EANM'23 - Annual Congress of the European Association of Nuclear Medicine, Vienna, Austria
Evaluation of brain 18F-FDG-PET imaging as a translational biomarker for therapeutic monitoring in creatine transporter deficiency
A. Soyer, S. Goutal, N. Ziani, L. Breuil, G. Hugon, A. Winkeler, C. Disdier, H. Benech, T. Joudinaud, A. Mabondzo, N. Tournier
EANM'22 - Annual Congress of the European Association of Nuclear Medicine
Direct comparison of the blood-brain barrier transport and vulnerability to P-glycoprotein-mediated drug-drug interaction of domperidone versus metoclopramide assessed using in vitro assay and pharmacokinetic PET imaging
L. Breuil, S. Goutal, A. Soyer, M. Goislard, V. Lebon, D. Audisio, A. Del Vecchio, F. Caille, N. Tournier
EANM'22 - Annual Congress of the European Association of Nuclear Medicine
Evaluation of synaptic density using SV2A PET imaging as a readout of depression and antidepressant response in a mice model of depression
C. Leroy, S. Goutal, I. Mendez-David, W. Saba, M. Goislard, M. Bottlaender, F. Caillé, A. Gardier, E. Corruble, V. Lebon, R. Colle, N. Tournier, D. David
EANM'22 - Annual Congress of the European Association of Nuclear Medicine
Validation of 2-Deoxy-2-[18F]fluorosorbitol (18F-FDS) repurposed as a PET imaging biomarker of Blood Brain Barrier integrity in vivo
HUGON Gaëlle, GOUTAL Sebastien, DAUBA Ambre, WINKELER Alexandra, NOVELL Anthony, TOURNIER Nicolas
EANM'21 Virtual - Annual Congress of the European Association of Nuclear Medicine
Imaging pharmacokinetics of [11C]glyburide with whole-body PET
MARIE Solène, CHALAMPALAKIS Zacharias, BREUIL Louise, BECQUEMONT Laurent, Maud GOISLARD, CAILLE Fabien, COMTAT Claude,
BOTTLAENDER Michel, TOURNIER Nicolas
Total Body PET meeting 2021, Virtual
Validation of [11C]glyburide as PET probe for imaging OATP function in humans
Marie S, Breuil L, Chamlampakis Z, Becquemont L, Caillé F, Comtat C, Bottlaender M, Tournier N
EANM'20, Annual Congress of the European Association of Nuclear Medicine, Virtual, October 2020
[18F]Crizotinib PET imaging to address the impact of the P-glycoprotein transport function at the blood-brain barrier on the brain delivery of the drug
F. Caillé, M. Sardana, M. Goislard, L. Breuil, M. Schou, G. Wrigley, N. Tournier, C. Elmore, B. Kuhnast
EANM'20, Annual Congress of the European Association of Nuclear Medicine, Virtual, October 2020
In vivo comparison of the sensitivity of PET radioligands to detect moderate changes in P-gp function at the blood-brain barrier
L. Breuil, F. Caillé, S. Marie, S. Goutal, S. Auvity, M. Goislard, C. Coulon, T. Lekieffre, W. Saba, N. Tournier
EANM'20, Annual Congress of the European Association of Nuclear Medicine, Virtual, October 2020
Ultrasound enhanced brain delivery of 89Zr-Cetuximab, an anti-EGFR based immunotherapy followed by immunoPET
A. Schweitzer-Chaput, A. Novell, N. Tournier, V. Tran, B. Jego, B. Larrat, C. Truillet
EANM'20, Annual Congress of the European Association of Nuclear Medicine, Virtual, October 2020
Application of a generic dynamic reconstruction algorithm on PET whole-body pharmacokinetic studies
Z. Chalampalakis, S. Stute, M. Filipovic, S. Marie, M. Bottlaender, N. Tournier, C. Comtat
EANM'20, Annual Congress of the European Association of Nuclear Medicine, Virtual, October 2020
Dynamic 4D PET reconstruction using the spectral model and adaptive residual modelling
Chalampalakis Z
2020 IEEE NSS MIC RTSD
Low dose of donepezil restores glucose metabolism in a mouse model of Alzheimer’s disease : a 18F-FDG positron emission tomography (PET) imaging study.
Hugon G,
EMIM
Refining the use of PET imaging to detect moderate change in P-glycoprotein function at the blood-brain barrier
Breuil L, Marie S, Goislard M, Caillé F, Tournier N
Society for the study of blood-brain interface, Orsay, December 2020
Strategies to improve imaging methods for the study of SLCO-transport function in vivo
Marie S, Tournier N.
Hepatocyte Transporter Network, Les Diablerets, Switzerland, September 2019
Imaging hepatic and extrahepatic OATP function: pharmacokinetic importance for drug delivery to tissues
Marie S, Auvity S, Stute S, Goutal S, Saba W, Bottlaender M, Kuhnast B, Tournier N
SFPT'19 - Congrès de la Société Française de Pharmacologie et de Thérapeutique, Lyon 2019.
Is there a risk for alcohol‐drug interaction involving P‐glycoprotein at the blood‐brain barrier? A PET imaging study using 11C‐metoclopramide in baboons
Auvity S, Marie S, Goutal S, Saba W, Caillé F, Tournier N
SFPT'19 - Congrès de la Société Française de Pharmacologie et de Thérapeutique, Lyon 2019.
11C-metoclopramide PET imaging to reveal and quantify the contribution of the P-glycoprotein to the clearance of its substrates from the brain
Auvity S, Marie S, Caillé F, Wimberley C, Bauer M, Langer O, Buvat I, Goutal S, Tournier N.
EANM'18, Annual Congress of the European Association of Nuclear Medicine, Germany, October 2018.
Towards an improved radiotracer to study P-glycoprotein function at the blood-brain barrier: first human PET data with [11C]metoclopramide
Bauer M, Tournier N, Auvity S, Pichler V, Nics L, Klebermass E-M, Hacker M, Zeitlinger M, Langer O.
EANM'18, Annual Congress of the European Association of Nuclear Medicine, Germany, October 2018.
Quantification of hepatic and extrahepatic OATP function using whole-body dynamic11C-glyburide PET imaging
Marie S, Stute S, Goutal S, Saba W, Bottlaender M, Kuhnast B, Tournier N.
EANM'18, Annual Congress of the European Association of Nuclear Medicine, Germany, October 2018.
Quantification of the efflux clearance role of the P-glycoprotein at the blood-brain barrier: a 11C-metoclopramide PET study in baboons
Auvity S, Marie S, Caillé F, Wimberley C, Bauer M, Langer O, Buvat I, Goutal S, Tournier N.
NRM’18 - The 11th International Symposium on Functional NeuroReceptor Mapping of the Living Brain.
P-glycoprotein (ABCB1) function at the blood-brain barrier drives the clearance of its substrates from the brain back to the blood: a 11C-metoclopramide PET study in baboons.
Auvity S, Marie S, Caillé F, Wimberley C, Bauer M, Langer O, Buvat I, Goutal S, Tournier N.
SNMMI'18 - – Annual meeting of the society of nuclear medicine and molecular imaging
Persistence of the ABC transporter-mediated efflux at the physically disrupted blood-brain barrier: a 11C-erlotinib PET imaging study in rats.
Goutal S, Auvity S, Gerstenmayer M, Caillé F, Buvat I, Larrat B, Tournier N
SNMMI'18 - – Annual meeting of the society of nuclear medicine and molecular imaging
Repurposing radiotracers for myelin imaging: a study comparing 11C-MeDAS, 18F-florbetapir and 18F-florbetaben with 11C-PiB.
Auvity S, Tonietto M, Caillé F, Bodini B, Bottlaender M, Tournier N, Kuhnast B, Stankoff B
SNMMI'18 - – Annual meeting of the society of nuclear medicine and molecular imaging
A barrier or a pump? Imaging the impact of P-glycoprotein function on the brain kinetics of metoclopramide in nonhuman primates.
Auvity S, Marie S, Caillé F, Wimberley C, Bauer M, Langer O, Buvat I, Goutal S, Tournier N.
SFPT'18 - Congrès de la Société Française de Pharmacologie et de Thérapeutique, Toulouse 2018.
Imaging the impact of OATP function on erlotinib exposure to tissues: a [11C]erlotinib PET imaging study in rats.
Amor D, Caillé F, Goutal S, Marie S, Goislard M, Auvity S, Tournier N.
SFPT'18 - Congrès de la Société Française de Pharmacologie et de Thérapeutique, Toulouse 2018.
Susceptibility to morphine-induced glial activation assessed using TSPO PET imaging with 18F-DPA-714 in nonhuman primates
Auvity S*, Saba W, Goutal S, Leroy C, Buvat I, Cayla, Caillé F, Bottlaender M, Cisternino S, Tournier N.
SNMMI’17– Annual meeting of the society of nuclear medicine and molecular imaging
Imaging the neuroimmune response to alcohol exposure in adolescent baboons: a TSPO PET study using 18F-DPA-714
Saba W, Goutal S, Auvity S*, Kuhnast B, Colon C, Kouyoumdjian V*, Buvat I, Leroy C, Tournier N.
SNMMI’17– Annual meeting of the society of nuclear medicine and molecular imaging
Mise en évidence de la réponse neuroimmunitaire associée à l’exposition aigue à la morphine par imagerie TEP au 18F-DPA-714, un radioligand de la TSPO
Auvity S*, Saba W, Goutal S, Leroy C, Buvat I, Cayla J, Caillé F, Bottlaender M, Cisternino S, Tournier N.
Journée Scientifique des Internes en Pharmacie - Scinphar (2017)
Apport de l’imagerie TEP pour l’étude et de l’exposition cérébrale de l’erlotinib et l’évaluation de stratégies d’optimisation de sa distribution cérébrale
Tournier N, Goutal S*, Auvity S*, Traxl A, Mairinger S, Wanek T, Buvat I, Soussan M, Caillé F, Langer O.
SFMN 2017 - Congrès annuel de la Société Française de Médecine Nucléaire
Diphenhydramine is a specific and selective probe to study the H+/antiporter function at the blood-brain barrier: application to 11C-diphenhydramine PET imaging
Auvity S*, Chapy H, Goutal S, Caillé F, Hosten B, Smirnova M, Tournier N, Cisternino S
NRM’16 - The 10th International Symposium on Functional NeuroReceptor Mapping of the Living Brain.
Young Investigator Award
Inhibition of P-gp and BCRP-mediated efflux transport of [11C]erlotinib at the non-human primate blood-brain barrier.
N. Tournier, S. Goutal, S*. Auvity, A*. Traxl, S. Mairinger, T. Wanek, I. Buvat, M. Soussan, F. Caillé, O. Langer.
EANM'16 - Annual Congress of the European Association of Nuclear Medicine.
Imaging drug-drug interaction using PET: investigating the impact of diazepam on buprenorphine-induced respiratory depression.
Vodovar D*, Pottier G, Auvity S*, Mégarbane B, Buvat I, Caillé F, Tournier N.
EANM'16 - Annual Congress of the European Association of Nuclear Medicine.
11C-metoclopramide PET imaging unveils a saturable carrier-mediated uptake by the liver with subsequent impact on metoclopramide metabolism and pharmacokinetics
Caillé F, Goutal S, Kuhnast B, Pottier G, Tournier N.
SNMMI’16– Annual meeting of the society of nuclear medicine and molecular imaging
11C-metoclopramide, an alternative PET radioligand to image P-glycoprotein function at the blood-brain barrier
Pottier G, Goutal S, Marie S*, Caillé F, Auvity S*, Peyronneau MA, Stute S, Dollé F, Boisgard R, Tournier N.
CBV 2015 - 11th International Conference on Cerebral Vascular Biology.
Influence of ABC-transporter function at the blood-brain barrier on the brain kinetics of PET radioligands
Tournier N, Bottlaender M., Cisternino S.
12th Annual French-Belgian ABC Meeting, October 3rd, Paris, 2014.
Imaging OATP2B1-mediated transport in the myocardium and lung
Tournier N, Goutal S, Grelier A*, Bottlaender M, SabaW, Valette H, Helal O.B, Damont A, Kuhnast B.
SNMMI’14– Annual meeting of the society of nuclear medicine and molecular imaging. J Nucl Med. 2014; 55 (Suppl. 1):328
Is 18F-pMPPF a P-glycoprotein substrate in human?
Tournier N, Valette H, Goutal S, Schöllhorn M, Saba W, Cisternino S, Scherrmann J.M, Bottlaender M.
EANM'10 - Annual Congress of the European Association of Nuclear Medicine. Eur J Nucl Med Mol Imaging 2010; 37 (Suppl. 2):S210
Poster presentations
Decreased opioid receptor availability and impaired neurometabolic coupling as a signature of morphine tolerance in rats : a PET study
Amelie Soyer* , Sarah Leterrier, Fabien Caillé ,Sophie Amargier, Maud Goislard, Claire Leroy, Wadad Saba, Gregory Dal-bo, Karine Thibault, Sebastien Goutal , Nicolas Tournier
EMIM, Porto, 2024
Best Poster Award
Brain PET imaging predicts the long-term behavioral impact of exposure to sublethal doses of organophosphates: a longitudinal study in mice exposed to NIMP, a sarin surrogate
Amelie Soyer , Sarah Leterrier, Alexandre Champault, 1, Maud Goislard, Sophie Amargier, Benoit Hosten, Sebastien Goutal, Alexandra Winkeler, Gregory Dal-bo, Karine Thibault, Nicolas Tournier
EMIM, Porto, 2024
Dynamics of the effects of ketamine on synaptic density: a longitudinal Positron Emission Tomography study in mice using 11C-UCB-J.
Corvo C*, Goutal S, Mendez-David I, Goislard1 L Amargier S, Leterrier. S, Leroy C, David DJ, Tounier N
EMIM, Porto, 2024
Comparison of [18F]DPA-714 PET imaging with [18F]FDG PET for pre-surgical localization of the seizure onset-zone in drug-resistant focal epilepsy
M. Cheval, C. Leroy, M. Bottlaender, F. Caillé, N. Tournier, A. Petrescu, D. Taussig, S. Rodrigo, V. Bouilleret
EANM'22 - Annual Congress of the European Association of Nuclear Medicine
Alcohol and tobacco: PET imaging using 2-[18F] fluoro-A-85380 unveils change in nicotinic receptor availability induced by ethanol exposure during adolescence
W. Saba, M. Goislard, L. Breuil, F. Caillé, N. Tournier
EANM'22 - Annual Congress of the European Association of Nuclear Medicine
Quantitative determination of blood-brain barrier permeability assessed using [18F]2-fluoro-2-deoxy-sorbitol as a feature of neuroinflammation in a mouse model of endotoxemia
S. Leterrier, S. Goutal, W. Saba, G. Hugon, M. Goislard, S. Specklin, V. Lebon, A. Winkeler, N. Tournier
EANM'22 - Annual Congress of the European Association of Nuclear Medicine
A multitracer approach using 11C-buprenorphine and 18F-FDG PET imaging to explore the neuropharmacology of buprenorphine in rats
A. Soyer, S. Leterrier, L. Breuil, F. Caillé, M. Goislard, C. Leroy, W. Saba, M. Bottlaender, S. Goutal, N. Tournier
EANM'22 - Annual Congress of the European Association of Nuclear Medicine
Immediate and delayed impact of transient blood-brain barrier disruption induced by focused ultrasound on the brain kinetics of11C-metoclopramide, a PET probe for P-glycoprotein
N. Tournier, S. Goutal, A. Novell, L. Breuil, E. Selingue, S. Leterrier, M. Gerstenmayer, S. Marie, F. Caillé, V. Lebon, C. Truillet, B. Larrat
EANM'22 - Annual Congress of the European Association of Nuclear Medicine
Targeted pharmacological inhibition and kinetic modelling to improve the performance of [99mTc]mebrofenin as probe to study MRP2 activity at the liver-bile interface
Marie S, Hernandez-Lozano I, Breuil L, Saba W, Goislard M, Novell A, Gennisson J-L, Langer O, Truillet C, Tournier N.
EANM'20, Annual Congress of the European Association of Nuclear Medicine, Virtual, October 2020
Nalmefene alleviates alcohol-induced neuroinflammation: a PET imaging study with [18F]DPA-714 in an adolescent rats
Saba W, Pottier G, Goislard M, Leroy C, Negroni J, Demphel S, Caillé F, Coulon C, Jaumain E, Jégo B, Tournier N
ESBRA 2019, European Society for Biomedical Research on Alcoholism, Lille 2019
Best Poster Award
Impact of global ultrasound-induced blood-brain barrier opening on the distribution of full monoclonal antibody cetuximab
Truillet C, Tran V, Novell A, Gerstenmayer M, Bouleau A, Nozach H, Kuhnast B, Tournier N, Larrat B
EANM'19 - Annual Congress of the European Association of Nuclear Medicine. Eur J Nucl Med Mol Imaging (2019) 46 (Suppl 1): S1–S952
Whole-body dynamic PET-MR imaging unveils the biodistribution and tissue kinetics of 11C-buprenorphine in humans
Pinon A, Leroy C, Caillé F, Gervais P, Jan S, Comtat C, Chalampalakis Z, Fernandez B, Bottlaender M, Tournier N
EANM'19 - Annual Congress of the European Association of Nuclear Medicine. Eur J Nucl Med Mol Imaging (2019) 46 (Suppl 1): S1–S952
A Simple And Quantitative Method To Address The Synchronicity Between Uptake And E ux Transporters In The Rat Liver Using 99mTc-mebrofenin Scintigraphy
Marie S, Hernández Lozano I, Breuil L, Langer O, Truillet C, Tournier N
EANM'19 - Annual Congress of the European Association of Nuclear Medicine. Eur J Nucl Med Mol Imaging (2019) 46 (Suppl 1): S1–S952
Tailoring the sensitivity of PET tracers to detect P-glycoprotein-mediated drug-drug interactions at the blood-brain barrier: a comparative in vitro study
Breuil L, Marie S, Goislard M, Langer O, Del Vecchio A, Audisio D, Caillé F, Tournier N.
EANM'19 - Annual Congress of the European Association of Nuclear Medicine. Eur J Nucl Med Mol Imaging (2019) 46 (Suppl 1): S1–S952
Neuropharmacokinetic impact of the P-glycoprotein-mediated efflux clearance property of the blood-brain barrier: first human PET data with 11C-metoclopramide
Tournier N, Bauer M, Auvity S, Marie S, Pichler V, Nics L, Klebermass E-M, Hacker M, Zeitlinger M, Langer O
SFPT'19 - Congrès de la Société Française de Pharmacologie et de Thérapeutique, Lyon 2019. Commented Poster
Evaluation of a strategy to enhance the brain distribution of erlotinib: a [11C]erlotinib PET imaging study in nonhuman primates
Goutal S, Auvity S, Buvat I, Caillé F, Langer O, Tournier N.
SFPT'18 - Congrès de la Société Française de Pharmacologie et de Thérapeutique, Toulouse 2018. Commented Poster
Imaging buprenorphine brain kinetics and target engagement using 11C-buprenorphine PET in nonhuman primates: quantitative correlation to pharmacological MRI data
Auvity S*, Leroy C, Goutal S, Buvat I, Bottlaender M, Caillé F, Tournier N.
NRM’16 - The 10th International Symposium on Functional NeuroReceptor Mapping of the Living Brain.
Imaging cationic drug H+/antiporter function at the blood-brain barrier using 11C-diphenhydramine PET imaging.
Auvity S*, Goutal S, Chapy H, Caillé F, Sirmnova M, Cisternino S, Tournier N.
SNMMI’16 Annual meeting of the society of nuclear medicine and molecular imaging
High dose erlotinib as an alternative to elacridar for the combined inhibition of ABCB1 and ABCG2 at the blood-brain barrier: an 11C-erlotinib PET study in nonhuman primates.
Tournier N, Goutal S*, Auvity S*, Traxl A, Mairinger S, Wanek T, Buvat I, Soussan M, Caillé F, Langer O.
SNMMI’16 Annual meeting of the society of nuclear medicine and molecular imaging.
Influence of morphine exposure and withdrawal on the brain kinetics of [18F]DPA-714 and classical biomarkers of inflammation
Auvity S*, Goutal S, Thésé B, Kuhnast B, Hosten B, Saba W, Boisgard R, Cisternino S, Tournier N. EANM’15 - 29th Annual Congress of the European Association of Nuclear Medicine.
Are there gender differences in P-glycoprotein function at the rat blood-brain barrier?
Marie S*, Pottier G, Goutal S, Auvity S*, Boisgard R, Dollé F, Caillé F, Tournier N.
EANM’15 - 29th Annual Congress of the European Association of Nuclear Medicine.
Imaging the P-gp inhibitor potency of dipyridamole at the blood-brain barrier using 11C-N-desmethyl-loperamide PET in nonhuman primates
Saba W, Damont A, Goutal S, Valette H, Auvity S*, Dollé F, Brulon V, Bottlaender M, Bertrand Kuhnast B, Tournier N.
CBV 2015 - 11th International Conference on Cerebral Vascular Biology.
Evaluation of 11C-metoclopramide in rat: a moderate P-glycoprotein substrate with suitable baseline brain uptake
Pottier G, Marie S*, Goutal S, Peyronneau MA, Caillé F, Stute S, Boisgard R, Dollé F, Tournier N.
SNMMI’15– Annual meeting of the society of nuclear medicine and molecular imaging.
Influence of P-glycoprotein inhibition at the blood-brain barrier on 18F-2-fluoro-2-deoxy-D-glucose (18F-FDG) brain kinetics
Goutal S, Saba W, Gervais Ph, Valette H, Brulon V, Bottlaender M, Tournier N.
SNMMI’15– Annual meeting of the society of nuclear medicine and molecular imaging.
Influence of ethanol on the brain binding of [18F]fluoro-A-85380: a PET study in Monkey
Saba W, Goutal S, Peyronneau MA, Dollé F, Coulon C, Leroy C, Tournier N, Valette H.
SNMMI’15 – Annual meeting of the society of nuclear medicine and molecular imaging.
Influence of morphine exposure and withdrawal on the brain kinetics of the TSPO radioligand [18F]DPA-714: a microPET study in rats
Auvity S*, Goutal S, Chaves C, Thézé B, Kuhnast B, Hosten B, Saba W, Boisgard R, Cisternino S, Tournier N.
BrainPET’15 - XIIth International Conference on Quantification of Brain Function with PET.
Relevance of the lithium-pilocarpine rat model for the study of P-glycoprotein overexpression during pharmacoresistant epilepsy
Marie S*, Pottier G, Caillé F, Goutal S, Boisgard R, Dollé F, Stute S, Hosten B, Jacob A, Tournier N.
BrainPET’15 - XIIth International Conference on Quantification of Brain Function with PET.
11C-glyburide PET imaging questions the role of OATP transporters at the blood-brain barrier
Tournier N, Saba W, Kuhnast B, Goutal S, Grelier A* , Bottlaender M, Cisternino S.
NRM’14 - The 10th International Symposium on Functional NeuroReceptor Mapping of the Living Brain.
Propofol and isoflurane anesthesia affect 18F-DPA-714 PET kinetics and in vitro binding parameters in Baboon
Saba W, Tournier N, Goutal S, Dollé F, Kuhnast B, Peyronneau MA, Valette H.
NRM’14 - The 10th International Symposium on Functional NeuroReceptor Mapping of the Living Brain.
[18F]CfO-DPA-714, a new TSPO radioligand: Preliminary in vivo/in vitro characterization in baboon
Saba W, Damont A, Kuhnast B, Goutal S, Tournier N, Cayla J, Dollé F, Valette H, Peyronneau M.A
SNMMI’14– Annual meeting of the society of nuclear medicine and molecular imaging.
Apport dosimétrique de l’enceinte de fractionnement de [18F]Fluorodésoxyglucose ([18F]FDG) Unidose® par rapport à la préparation manuelle des seringues en enceinte blindée de classe A
Kouyoumdjian V*, Tournier N, Coulon C, Lekieffre T, Coutreau C, Renard G, Gervais Ph.
9èmes Rencontres Convergences Santé Hôpital (2014)
The novel pyrazolo[1,5-a]pyrimidineacetamide, [18F]CfO-DPA-714, a potential PET ligand of the TSPO: Metabolism in rodents and non-human primates
Peyronneau M, Damont A, Saba W, Goutal S, Tournier N, Kassiou M, Dolle, F Valette H.
EANM’12 – Annual Congress of the European Association of Nuclear Medicine.
Inhalation of cigarette smoke decreases the binding of [18F]DPA-714 to 18 kDa translocator protein (TSPO) in several tissues: a PET study in baboons
Saba W, Peyronneau M, Goutal S, Damont A, Dollé F, Tournier N, Valette H.
EANM‘12 - Annual Congress of the European Association of Nuclear Medicine. Eur J Nucl Med Mol Imaging. 2012; 39 (Suppl. 2):S412
Understanding the effects of the P-gp inhibitor cyclosporin on 18F-MPPF brain uptake in nonhuman primate
Tournier N, Saba W, Bottlaender M, Dollé S, Cisternino S, Goutal S, Peyronneau MA, Valette H.
BrainPET’11 - XIIth International Conference on Quantification of Brain Function with PET.
Carbon-11-labelling of a novel, trishomocubane-derived, high affinity and selectivity DAT ligand
Dolle F, Le Helleix S, Peyronneau M, Saba W, Banister S, Tournier N, Valette H, Kassiou M.
ISRS’11 - International Symposium on Radiopharmaceutical Sciences. J Label Compounds Radiopharm. 2011;54 (Suppl.1): S276
Radiosynthesis of [11C]glyburide for in vivo imaging of BCRP function with PET
Kuhnast B , Damont A, Tournier N, Saba W, Valette H, Bottlaender M, Dollé F.
ISRS’11 - International Symposium on Radiopharmaceutical Sciences. J Label Compounds Radiopharm. 2011;54 (Suppl. 1): S262
Evaluation of 11C-glyburide as a PET probe for P-gp and Bcrp transport imaging at the mouse BBB
Tournier N, Saba W, Kuhnast B, Damont A, Dollé F, Peyronneau MA, Valette H, Cisternino S, Bottlaender M.
SNMMI’11 – Annual meeting of the society of nuclear medicine and molecular imaging. J Nucl Med. 2011; 52 (Suppl. 1):1566
Effect of P-glycoprotein on 18F-FDG brain transport
Tournier N, Andre P, Valette H, Scherrmann J.M, Cisternino S, Bottlaender M.
Gordon Research conferences (2010) – Barriers of the CNS - Blood/Brain Interfaces in health and disease.
In vitro screening of PET radiotracers transport by human P-glycoprotein and Breast Cancer Resistance Protein
Tournier N, Scherrmann J.M, Bottlaender M.
EANM’09 - Annual Congress of the European Association of Nuclear Medicine. Eur J Nucl Med Mol Imaging. 2009; 36 (Suppl. 2):S472-3
Interaction of drugs of abuse and maintenance treatments with human P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2)
Tournier N, Chevillard L, Megarbane B, Scherrmann JM, Decleves X.
AAPS 2009 – Annual congress of the American Association of Pharmaceutical Scientists.
Influence of P-glycoprotein, Mrp1, Bcrp and membrane potential on the Tc-sestamibi transport at the mouse blood-brain barrier
Cattelotte J, Tournier N, Cisternino S, Scherrmann JM.
AAPS 2007 - Annual congress of the American Association of Pharmaceutical Scientists
Mise au point d’une méthode in vitro d’identification des molécules radiomarquées substrats de la P-glycoprotéine
Duez C, Tournier N, Rizzo-Padoin N, Leverge R, Scherrmann J.M.
29ièmes Journées de l’association de pharmacie hospitalière de l’Ile de France (2007) – Best Poster Award
Variabilité du rendement de marquage du Nanocis par le 99mTc: influence du volume du milieu réactionnel
Tournier N, Chan D, Dumont A, Devaux J-Y, Prugaud J-L.
Congrès annuel du syndicat national des pharmaciens hospitaliers et praticiens hospitaliers universitaires (2006).
Intérêt de l’enregistrement dynamique du transit gastrique
Maurel G, Tournier N, Coutris G, Devaux J.Y.
Colloque de la société française de médecine nucléaire et d’imagerie moléculaire (2006).
Etude de la stabilité chimique d’une préparation d’amiloride à 1,5 mg/mL en solution aqueuse stérile
Tournier N, Do B, Korb V, Djoussa S, Gimenez F, Corriol O, Singlas E.
27ièmes journées l’association de pharmacie hospitalière de l’Ile de France (2005).
Synthèse et purification de l’ibogaïne radiomarquée au technetium-99m
Tournier N, Du Moulinet d’Hardemare A, Cisternino S, Rizzo-padoin N, Scherrmann JM, Leverge R.
Congrès annuel du syndicat national des pharmaciens hospitaliers et praticiens hospitaliers universitaires (2005).